Research Scientist – Molecular Biology

Integral Molecular

Integral Molecular is a Philadelphia biotech company specializing in the discovery and characterization of therapeutic antibodies using cutting-edge technology platforms. We are a close-knit company composed of smart, curious scientists that takes an active interest in promoting the learning and development of our team. 

Research Scientist – Molecular Biology ID# 05022023 

Our company is in an exciting growth phase where we are launching new products, expanding our team, and reaching new markets. We seek a deeply scientifically curious scientist to join a diverse, interactive, collaborative, and highly supportive molecular biology team. The Molecular Biology scientist, under the supervision of the Molecular Biology Project Leader will join our team of researchers to create new constructs that are the cornerstone of all projects within the company. Everything starts with a plasmid! 

In addition, this role will interact with other internal teams and partners to understand their projects and provide scientific guidance on appropriate scope of work using Integral Molecular technologies and platforms. 

What you will gain from working at Integral Molecular: 

• Learn high-throughput design and cloning approaches  

• Develop insights into business models for product delivery in virology, antibody, and pre-clinical spaces 

• Gain a deeper understanding of virology and discover how Integral Molecular RVP technologies support critical vaccine development 

• Learn new techniques such as flow cytometry, protein engineering, and viral infectivity assays 

• Technical and team leadership opportunities 

• Ability to grow and thrive in a fast-paced, collaborative environment 

What you will do at Integral Molecular: 

• Perform molecular cloning including high-throughput plasmid generation 

• Design plasmid constructs for the expression of viral and membrane proteins in support of customer projects and for the development of internal research priorities including epitope mapping applications 

• Design experiments and guide troubleshooting for testing expression constructs  

• Collaborate extensively with internal teams to design and develop experiments that ensure constructs meet customer and internal requirements  

• Provide technical expertise and support to internal teams on molecular design and plasmid construction 

• Mentor junior team members in support of their technical and scientific development 

• Be an active participant at team and company meetings  

The successful candidate will have: 

Education 

• PhD in Biology, Biochemistry, Bioinformatics, Virology, or a related field 

Experience 

• Extensive prior experience with plasmid design, construction using restriction enzyme, homologous recombination, PCR and other standard techniques  

• Ability to work with minimal supervision and be highly organized 

• Demonstrated ability as an individual contributor, as well as ability to work cooperatively within a team 

• Adaptable to quickly shifting priorities 

Additional experience desired but not necessary:

• Experience with heterologous or recombinant membrane protein expression 

• Familiarity with flow cytometry, viral particle production, and/or antibody production 

• Experience conducting high-throughput assays