Vice President, Market Access and Channel Strategy
Job Details
Full Time
4 Year Degree
Up to 50%

Company Summary: Aeglea is a clinical-stage biotechnology company that engineers next-generation human enzymes with enhanced properties and novel activity to provide solutions for diseases with unmet medical need. Aeglea is developing pegzilarginase, its lead product candidate, for the treatment of Arginase 1 Deficiency which has received both Rare Pediatric Disease and Breakthrough Therapy Designation. Aeglea has two programs in IND-enabling studies for Homocystinuria and Cystinuria and an active discovery pipeline.


Position Summary: Aeglea BioTherapeutics, based in Austin Texas, is recruiting for a Vice President, Market Access and Channel Strategy. This individual is responsible for providing strategic leadership for all product distribution, pricing, reimbursement and access (PRA) activities for Aeglea’s pipeline and commercial products; delivering and executing against strategic PRA-related insights for launch planning activities; and ensuring seamless collaboration with cross-functional groups including patient services, marketing, sales, HEOR, analytics, finance, and medical affairs teams.  This position will build and lead a high-performing Market Access and Distribution team that provides solutions to ensure that appropriate patients have access to Aeglea’s approved therapies. As a member of the commercial leadership team, this position will work across the organization to ensure that market access and distribution efforts are aligned with corporate and project-level deliverables.


Essential Duties and Responsibilities: To perform this job successfully, an individual must be able to perform the following:

  • Lead the development and implementation of Aeglea’s channel distribution strategy including management of 3PL, specialty distributors, specialty pharmacies with a high level of collaboration with cross-functional stakeholders including patient services
  • Develop PRA strategies consistent with the product’s overall value proposition to ensure patient access to therapy and long-term commercial success
  • Play a leadership role in forecasting and managing key variables related to product-level gross-to-net calculations
  • Collaborate with Medical Affairs and HEOR to ensure the creation and communication of disease state and product information that establishes a compelling value proposition to key market access stakeholders and partners
  • Guide and shape strategic PRA decisions through a combination of insights from previous experience, market research, product analogs, and secondary data sources
  • Develop and assess metrics and key performance indicators to ensure success of market access strategy and activities
  • Build and lead a highly experienced Market Access team while overseeing the execution of multiple strategies to attain strategic objectives in all areas of market access
  • Develop and manage departmental budgets that effectively achieve desired commercial goals while balancing the financial objectives of the overall organization
  • Oversee the coordination and success of key external vendors and agencies to ensure project success
  • Partner with internal program leadership teams and corporate development to evaluate PRA strategies for internal pipeline programs and external partnership opportunities
  • Ensure compliance with corporate policies and procedures as well as all relevant healthcare laws and regulations

To perform this job successfully, an individual must be able to perform each essential duty. The requirements listed below are representative of the knowledge, skill, and/or ability required.


Education/Experience: The ideal candidate will offer:

  • Bachelor’s degree required; MBA, scientific degree or other advanced degree preferred
  • 10+ years of progressive experience in managed markets roles in account management, formulary access, contract negotiations and policy development
  • 7+ years national and regional direct account management or oversight across multiple payer types


Knowledge, Skills and Abilities:

Technical Expertise

  • An advanced understanding of the drug development process
  • Leading edge knowledge of the principles, concepts, practices, and theories of payer strategies across all applicable segments including commercial, Medicare Part B&D, Medicaid, and Federal systems (VA, DOD) and Commercial activities. Along with advanced knowledge of the principles and concepts of other cross-functional disciplines
  • Advanced knowledge of reimbursement and strong understanding of health insurance and benefits, co-pay assistance programs, Medicare, Medicaid, and private payer policies
  • Breadth and depth of experience managing the Market Access responsibilities associated with managing a portfolio of complex programs
  • Ability to apply technical and line knowledge to plan/design and manage projects within a matrix team dynamic
  • Strong analytical skills, project/launch planning, and organizational skills
  • Strong understanding of legal, compliance, and regulatory environment in the pharmaceutical industry
  • Strong understanding of key HEOR principles and evidence dossier

Teamwork and Collaboration

  • Ability to develop and leverage constructive relationships across disciplines, functions and externally with a broad variety of people; establishes and maintains professional and productive working relationships with team members
  • Advanced interpersonal, active listening, and influencing skills; able to coach others
  • Breadth and depth of experience in interacting with cross-functional study team members, lines and senior managers


  • Effective decision-making skills that may require developing innovative options and/or multiple solutions to resolve complex problems
  • Comfortable with ambiguity and can drive towards implementation in a fast paced and evolving environment
  • Recommends potential courses of action to management and/or senior leaders that impact across lines and programs throughout the organization
  • Provides and leads in-depth analyses and recommendations to management and leaders in complex situations across the function


  • Ability to initiate, plan and organize complex projects and work independently using knowledge and work experience in ambiguous situations across programs
  • Ability to apply business knowledge to effectively assess and manage/mitigate risks to advance innovative processes and methodologies
  • Ability to multi-task, and work effectively under pressure; lead and adapt to change as needed; possess excellent project management skills; attentive to details
  • Ability to communicate with and influence teams to set realistic yet challenging timeline expectations; demonstrated ability to deliver within agreed internal timelines; monitor, manage and communicate progress against milestones, dealing with complex issues and escalating appropriately
  • Exercises foresight and judgement utilizing comprehensive breadth and depth of knowledge and prior work experience to lead others on complex projects


  • Influence and champion the development and direction of Access, Reimbursement, Channel Strategies and the Commercial team to best support Aeglea
  • Visionary in understanding and creating an environment that fosters innovation and creative thinking


Work Environment

This is a high growth, fast paced, and small organization. The ability to be productive and successful in a scientifically led and data driven work environment is critical. Willingness and ability to travel domestically, and internationally on occasion may be required, up to 50% of work time.


Physical DemandsThe physical demands described here are representative of those that must be met by an employee to successfully perform the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.


Light physical activity performing non-strenuous daily activities of an administrative nature. Including but not limited to: Sitting for greater than 75% of your time, standing and walking for up to 25% of your time. Manual dexterity sufficient to reach/handle items and work with the fingers. Use of hands to fingers for typing and other computer activity for up to 75% of your time. Reaching with hands and arms, climb or balance, stoop, kneel, crouch, or crawl less than 25% of your time. Ability to lift, up to 25lbs, less than 25% of the time.


The above job description is not intended to be an all-inclusive list of duties and standards of the position.  Incumbents will follow any other instructions, and perform any other related duties, as assigned by their supervisor.