Research Analyst I
Job Details
Corporate Headquarters - Plymouth Meeting, PA
Full Time
Master's degree required

POSITION SUMMARY Join our team of research analysts in clinical evidence analysis who identify and analyze data about the clinical validity and utility of genetic tests and the effectiveness of gene therapies available for use in clinical care. This person will use the PICOTS analytic framework to analyze published studies, assess strength of evidence (using the GRADE-based system), and write rapid and in-depth evidence assessments on topics such as genetic tests, gene therapies, and other topics. Decision makers using these reports include genetic counselors and clinical policy makers at third-party payers and health systems who make evidence-based decisions about appropriate use. The person in this role will also help to identify and prioritize new topics and stay abreast of trends in precision medicine likely to affect patient care.


Reasonable Accommodations Statement

To accomplish this job successfully, an individual must be able to perform, with or without reasonable accommodation, each essential function satisfactorily. Reasonable accommodations may be made to help enable qualified individuals with disabilities to perform the essential functions. 

Essential Functions Statements(s)

  • Learn the appropriate methods for analyzing clinical studies on diagnostics and therapeutics used in precision medicine
  • Use search results provided by medical librarians to select appropriate data for analysis, perform analysis, and write evidence assessments
  • Understand and apply concepts of PICOTS analytic framework and GRADE strength of evidence assessment in report preparation
  • Ensure understanding of client research requests on topics of interest
  • Meet deadlines for client deliverables
  • Apply biostatistical concepts to accurately analyze and present data in the assessments
  • Participate in making recommendations for prioritization of topics for evidence reports
  • Understand factors that affect diffusion of genetic tests and precision therapies
  • Understand audience perspectives (e.g., payer, health system, patient) and write at appropriate level for audience
  • Produce accurate analyses written clearly in active voice for intended audiences
  • Use peer review feedback to revise assessments as needed after review; document responses to reviewers and revisions to drafts
  • Use internal workflow tools (e.g., SharePoint) to follow appropriate procedures for report documentation, drafting, peer review, revision and final publication
  • Attend training sessions for analytic methods and report writing to inform your work as recommended by management
  • Weekly peruse major medical journals (e.g., JAMA, Nature, Lancet, New England Journal of Medicine), health sections of major news outlets (e.g., GenomeWeb, Fierce newsletters), and other publications related to precision medicine to identify “recommended readings” for client base.
  • Gain and maintain currency on state and federal regulatory issues affecting genetic test clearances/approvals, diffusion and utilization
  • Be thorough and attentive to detail; document sources for all facts and information used in reports and use the internal citation system workflows to request and document resources used
  • Participate in weekly team meetings, department meetings, and ECRI Town Hall meetings
  • Contribute to quality improvement and efficiency initiatives
  • Suggest ideas and themes for education on precision medicine and genetic testing that would interest clients
  • Embrace and demonstrate commitment to ECRI core values and culture of diversity and inclusion: compassion, integrity, impact, transparency, and innovation.

Accountability Metrics:

Annual metrics after completing 9 months’ training:

  • Depending on the type and depth of assessments required by clients, author some combination of the following as determined by client needs and management: 40 clinical evidence assessments or 100 curated bibliographies or a combination of the two
  • Identify 3 recommended readings per week for our client base
  • Attend or participate in relevant ECRI webinars, conferences, trainings to grow/maintain knowledge base as recommended by management
  • Professional development: Take relevant online education courses through LinkedIn learning to grow your knowledge base


  • Strong analytic and critical thinking skills coupled with familiarity with concepts of evidence-based medicine (e.g., related to precision medicine topics), systematic review, clinical study design and analysis of screening and diagnostic technologies; biostatistics; issues related to how genetic tests diffuse into clinical care.
  • Ability to write clearly and accurately to convey key findings from analyses in reports
  • Ability to: learn and use PICOTS framework to formulate appropriate key questions; understand clinical trial design for diagnostic technologies and assess risk of bias in studies; clinical data analysis; apply GRADE concepts to assess strength of evidence and draw conclusions; if needed, perform basic statistical tests on study data, accept and appropriately implement peer review critiques; and write accurately and clearly for health system and health plan audiences.

Education: Master or post-master degree in a nurse practitioner, physician assistant, or pharmacology program plus 3 years’ experience in a healthcare environment, or PhD in a life science (e.g., human genetics, molecular biology, cell biology, virology, immunology).

Computer Skills: Proficient with Microsoft Office 2016+

Certifications & Licenses: If applicant has graduated from a clinical program (nurse practitioner or physician assistant), must have and maintain current license.


N (Not Applicable)

Activity is not applicable to this position.

O (Occasionally)

Position requires this activity up to 33% of the time (0 - 2.5+ hrs/day)

F (Frequently)

Position requires this activity from 33% - 66% of the time (2.5 - 5.5+ hrs/day)

C (Constantly)

Position requires this activity more than 66% of the time (5.5+ hrs/day)

Physical Demands


O                                           Lift/Carry


F                                             10 lbs or less      O


C                                            11-20 lbs             N

Manually Manipulate

C                                            21-50 lbs             N


O                                            51-100 lbs           N

Reach Outward

O                                            Over 100 lbs       N

Reach Above Shoulder



C                                             Push/Pull


N                                             12 lbs or less       N                                   


N                                             13-25 lbs             N

Squat or Kneel

N                                             26-40 lbs             N


N                                             41-100 lbs           N

Other Physical Requirements

  • Vision (Near)


       Remote home office with frequent audiovisual interactions with team over collaboration software; physically attend headquarter location as needed


Equal Opportunity Employer-Disability and Veteran