Senior Scientist, Protein
Job Details
Waltham, MA - Waltham, MA
Full Time
Master's Degree

By joining Exosome Diagnostics, a Bio-Techne brand (NASDAQ: TECH), you will have an impact on future cutting-edge research. Exosome Diagnostics is a liquid biopsy company that harness the power of Exosomes as a multi-analyte component of Liquid Biopsies. Bio-Techne, and all of its brands, provides tools for researchers in Life Sciences and Clinical Diagnostics. Bio-Techne, and all of its brands, provides tools for researchers to further treat and prevent disease worldwide.

Exosome Diagnostics is seeking a Senior Scientist with proven experience in assay development, particularly involving immuno-affinity-based methods in protein science and technology, as well as a hands-on familiarity with working with nucleic acids.  This position requires an individual with a can-do attitude who is adaptable and able to fill different roles and responsibilities.  The ideal candidate has a documented track record and experience in a variety of protein detection and analytical methods, preferably in an industrial setting and/or under a regulated environment, highly organized with attention to details and have excellent communication skills.



  1. Serves as an in-house subject matter domain expert in protein science and technology.
  2. Provides technical leadership in immunoassay development and validation.
  3. Designs, innovates and executes protein-based assays including ELISA and other protein detection methods.
  4. Develops work routines including automation and standard operating procedures.
  5. Develops, supports or validates custom immunoassay products in CLIA or FDA-regulated setting if necessary.
  6. Leads or supports in-house development of technology solutions to interrogate exosome protein cargos.
  7. Leads or supports custom projects for biomarker discovery including using proteomics platforms.
  8. Reports and documents, in a timely manner, results, progress to colleagues and/or clients or for IP filing.
  9. Contributes and writes experimental plans, protocols, SOPs and reports accurately and on time.
  10. Leads or supports troubleshooting activities leading to resolution and improvement.
  11. Takes on routine laboratory responsibilities and be compliance with laboratory rules.
  12. Provides writing and technical support for SOPs, protocols, and Statements of Work as needed.
  13. Participates in the review and update of existing procedures and develop new procedures as needed.
  14. Follows company policies and practices, performs additional duties as assigned.


Knowledge, Skills, and Abilities:

  1. PhD in life sciences with 8+ years of experience in a molecular biology laboratory or medical testing lab, preferably in the biotech industry.
  2. 6+ years of hands-on experience in immunoassay development or protein science.
  3. Broad experience with a variety of protein detection and characterization instruments/platforms/technologies/chemistries.
  4. Experience isolating and characterizing exosomes, exosomal proteins and cargo.
  5. Ability to work seamlessly in a team and within an interdisciplinary environment.
  6. Experience with antibody validation techniques (strategies), immunoprecipitation, etc.
  7. Familiarity with commercial protein immunoassay reagents kits and platforms.
  8. Experience with PCR based nucleic acid detection techniques (e.g. qRT-PCR).
  9. Versed in molecular biology and standard immunological and protein methods.
  10. Experience with conjugation chemistry techniques
  11. Experience in cancer biology and/or neuroscience is a plus.
  12. Excellent communication skills and can implement technologies developed from R&D into a regulated environment.
  13. Self-motivated with the know how to prioritize and schedule multiple concurrent projects.
  14. Prior experience working with biofluids and cell free DNA is a plus.
  15. Prior experience working in a regulated environment is a plus.
  16. Prior experience in assay automation is also a plus.
  17. Excellent work ethic with high-level of professionalism and integrity.
  18. Excellent time management skills (timelines, schedules, task prioritization).

Why Join Bio-Techne:

  • We offer competitive salaries along with extensive medical, vision, and dental plans for you and your family starting on day one!
  • We invest in our employees’ financial futures through 401k matching and an employee stock purchase plan.
  • We help our employees develop their careers through mentorship, promotional opportunities, training and development, internship programs, tuition reimbursement, and more.
  • We offer employee resource groups, volunteer paid time off, employee events, and charity drives to build a culture of caring and belonging. 
  • We foster a culture of empowerment and innovation, where employees feel valued and encouraged to bring their new ideas to the table.

Where permitted by applicable law, candidate must have received or be willing to receive an FDA authorized COVID-19 vaccine by date of hire to be considered for this position

Bio-Techne is an E-Verify Employer in the United States.